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Gut bacteria byproducts may control appetite and blood sugar

NCT ID NCT06686888

First seen Feb 27, 2026 · Last updated Jun 20, 2026 · Updated 14 times

Summary

This study tested whether short-chain fatty acids (SCFAs) released in the small intestine or colon affect hunger-related hormones. Twenty-eight healthy adults took capsules containing SCFAs or a placebo, and their blood was sampled over eight hours. The goal was to see if where SCFAs are delivered changes hormone release, which could inform future appetite and metabolism treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • KU Leuven

    Leuven, 3000, Belgium

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

short-chain fatty acids (SCFA) as dietary supplements

What this could lead to

If successful, this could help design better dietary strategies to control appetite and blood sugar.

What could go wrong

This is a small, early-stage study in healthy people, so results may not apply to those with medical conditions. It only measures short-term effects.

Conditions

The condition(s) this trial relates to.

metabolic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.