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Shampoo that soothes the scalp may also help you sleep better

NCT ID NCT07680608

Symptom relief Sponsor: Zentrela Inc. Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 02, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This pilot study investigates whether using Nizoral® Daily Prevent shampoo and conditioner at least three times a week for two weeks can improve scalp comfort, sleep quality, and mood in adults who have both scalp discomfort and trouble sleeping. Participants wore a wrist sleep tracker, answered questionnaires, and had non-invasive brain activity measurements. The goal is to see if a simple cosmetic routine can have broader benefits for well-being.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Nizoral® Daily Prevent shampoo and conditioner
What this could lead to
If it works, this could point toward a simple, non-drug way to improve sleep and mood by easing scalp discomfort.
What could go wrong
This is a small pilot study with only 21 participants and no control group, so results may not be generalizable. The intervention is cosmetic, not medicinal, so any benefits are likely modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

21 people

The number who actually took part.

Started

Nov 2025

Finished

Feb 2026

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants were recruited from an existing volunteer database maintained by the research site in Hamilton, Ontario, Canada. The study population consisted of community-dwelling adults interested in participating in consumer product research. Recruitment was conducted through database outreach and screening questionnaires. Participants were selected from the local community and represented a range of ages and both sexes.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18 years or older. 2. Reported at least one scalp symptom within the past 2 weeks, such as itching, dryness, sensitivity, redness, or flakes. 3. Experienced scalp discomfort occasionally or more often during the past 2 weeks. 4. Reported a scalp discomfort rating of 4 or higher on a 0-10 scale. 5. Reported difficulty falling asleep or staying asleep within the past 2 weeks. 6. Experienced sleep difficulty more than once per week. 7. Willing and able to use the study shampoo and conditioner at least 3 times per week during the study. 8. Willing and able to wear a Fitbit sleep-tracking device during the study. 9. Able to attend all scheduled study visits. 10. Able to provide informed consent. Exclusion Criteria: 1. Current use of medicated scalp treatments or use within the previous 14 days. 2. Known allergy or sensitivity to ingredients commonly found in shampoos or conditioners. 3. Ongoing scalp conditions, including active psoriasis, eczema, or open sores. 4. Use of sleep aids, sedatives, antihistamines, or other medications that affect sleep more than once per week during the previous 2 weeks. 5. Participation in another clinical, cosmetic, or consumer research study within the previous 30 days. 6. Any condition that, in the opinion of the investigators, could interfere with study participation, compliance with study procedures, or interpretation of study results.

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Conditions

The condition(s) this trial relates to.

Dandruff pityriasis simplex

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dandruff

Contacts and locations

Locations

  • Zentrela Inc.

    Hamilton, Ontario, L8P 1J4, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.