Shampoo plus conditioner: the secret to fighting dandruff?
NCT ID NCT07133334
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether using a special anti-dandruff shampoo plus conditioner works better than shampoo alone for people with moderate to severe dandruff. Eighty participants used the products three times a week for four weeks, then were followed for 12 more weeks. Researchers measured dandruff levels and discomfort like itching to see which routine was more effective.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Selenium disulfide and piroctone olamine (anti-dandruff shampoo and conditioner)
- What this could lead to
- If the routine works better, it could offer a more effective way to manage dandruff and reduce discomfort like itching.
- What could go wrong
- This is a small, completed study with only 80 participants. The results may not apply to everyone, and any benefit might be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
80 people
The number who actually took part.
- Started
-
Apr 2025
- Finished
-
Sep 2025
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with moderate to severe dandruff in Quatre-Borne in Mauritius
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * At baseline: A moderate to severe level of squames: Total squames score (adherent + non-adherent) \> 4 (ranging from 0 to 10) including an adherent squames score ≥ 2.5 (ranging from 0 to 5) and no limit for non-adherent squames score at inclusion (groups must be equilibrating); * Patient with hair length \> 2 cm; * Patient having received the information about the study modalities and having given his/her written consent and having signed the "informed consent form" specific for this study, in accordance with the corresponding procedure; * Patient usually using a shampoo 2 to 3 times a week and accepting to follow this rate during the whole study period; * Patient having stopped any possible soothing, anti-dandruff and anti-hair loss treatment (per os or topical) 2 weeks prior to study beginning D-14; * Patient agreeing not to use any other hair product other than the ones provided for the study (till the end of study) in particular: * no styling product (tonic, spray, lotion, foam) three days before the study visit; * no treating haircare product (conditioner, hair mask, non-rinsed hair care product, oil,….); * no anti-scales products (whatever the type: shampoo, treatment..); * no hair colouring or hair bleaching within one week prior to any study visit. Exclusion Criteria: * Subject with psoriasis; * Pregnancy, breast feeding, childbearing potential without adequate contraception, or irregular menstrual cycles; * History of drug or alcohol abuse; * History or suspicion of unreliability, poor cooperation or noncompliance with medical treatment; * Topical treatment of the scalp with other antifungal medication or with corticosteroids in the last 3 weeks before start of the study; * Systemic use of retinoids, erythromycin, tetracycline or any of its derivatives, trimethoprim/sulfamethoxazole, or metronidazole within 28 days before the start of the study. * Likelihood of requiring treatment during the study period with drugs not permitted by the study protocol; * Clinical signs and/or history of immunosuppression; * Severe disease (e.g. cancer, cardiac infarct, unstable angina pectoris); * Treatment with any other investigational drug in the 4 weeks prior to study entry.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Eurofins
Quatre Bornes, Mauritius
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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