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Scientists probe muscle stem cells under low oxygen – no treatment yet
NCT ID NCT07341165
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how muscle stem cells (satellite cells) respond to a single session of eccentric leg exercise in healthy young men. Participants exercised in either normal air, a low-oxygen room, or with a blood-flow restriction cuff. Muscle biopsies and blood samples were taken at several time points to track cell changes. The goal was to better understand the basic biology, not to test a treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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38 people
The number who actually took part.
- Started
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Apr 2023
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 49 years
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy man * Aged between 20 and 49 years * Physically active * Not involved in resistance training, * No exposed to high altitude (\>1500m) 1 month before experiment Exclusion Criteria: * Intake of AINS, * Illness with altered inflammatory status, * Condition that prohibits resistance exercise (muscle injury) or the sampling of tissue biopsies (aspirin, anticoagulants, allergy to lidocaine)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculté des Sciences de la Motricité
Louvain-la-Neuve, 1348, Belgium
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Other studies related to the condition(s) this trial covers.
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