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Healthcare worker COVID study completed: key insights on transmission

NCT ID NCT04336215

Knowledge-focused Sponsor: Rutgers, The State University of New Jersey Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study followed 829 people, including healthcare workers and a comparison group, over several years to understand how SARS-CoV-2 spreads and who gets sicker. Researchers collected swabs, blood, and saliva samples along with survey data. The goal was to identify risk factors for infection and severe disease to better protect healthcare workers and the public.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help identify which healthcare workers are at highest risk for COVID-19 and how the virus spreads, leading to better protection strategies.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly lead to new therapies. Results may not apply to other settings or populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

829 people

The number who actually took part.

Started

Apr 2020

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

* HCW from two RBHS hospitals: Robert Wood Johnson University Hospital (RWJUH) in New Brunswick and University Hospital (UH) in Newark ; (both hospital presidents have approved the study) * NHCW from Rutgers faculty, staff, and hospital employees without patient contact;

Ages

20 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 20 years and older * Hospital and RBHS healthcare workers who have regular direct patient contact (≥3 patients/shift) in emergency rooms or inpatient settings that is expected to continue regularly over the next ≥3 months and who work ≥20 hours in the hospital weekly (residents, clinical fellows, attending physicians, nurse practitioners, physician assistants, registered nurses, license practice nurses, medical technicians, respiratory therapists, physical therapists, clinical pharmacists, dentists, dental hygienists, or dental assistants) * Hospital workers who do not have patient contact and non-healthcare from the Rutgers faculty, postdoctoral students, administrators, and staff. Exclusion Criteria: * Previous diagnosis with COVID-19 * Pregnant or have been diagnosed with a new medical condition in the past 30 days or have had a change in medications in the past 30 days * Participants who have been hospitalized in the past 30 days, had and had an emergency room, urgent care visit, or have had surgery. * Participants who have a fever on the day of their first visit to the study site (for consent, biospecimen collection, etc.).

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Conditions

The condition(s) this trial relates to.

Coronavinae infectious disease COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Coronavirus SARS-CoV-2

Contacts and locations

Locations

  • Clinical Research Center Rutgers-Robert Wood Johnson Medical School RWJUH East Tower -

    New Brunswick, New Jersey, 08901, United States

  • Clinical Research Unit Rutgers New Jersey Medical School

    Newark, New Jersey, 07103, United States

  • Environmental and Occupational Health Sciences Institute

    Piscataway, New Jersey, 08854, United States

  • RUCDR Infinite Biologics

    Piscataway, New Jersey, 08854, United States

  • Robert Wood Johnson University Hospital

    New Brunswick, New Jersey, 08901, United States

  • Rutgers School of Dental Medicine

    Newark, New Jersey, 07103, United States

  • University Hospital

    Newark, New Jersey, 07103, United States

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