Can radiation reignite cancer control after immunotherapy fails?
NCT ID NCT02710253
First seen Nov 10, 2025 · Last updated Jun 20, 2026 · Updated 28 times
Summary
This phase II trial tests whether radiation therapy can help control cancer that has spread or grown after immunotherapy. About 230 patients with metastatic or lymphoid cancers will receive targeted radiation to see if it stabilizes the disease or shrinks tumors. The study also monitors side effects to find the best dose.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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MD Anderson League City
League City, Texas, 77573, United States
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MD Anderson West Houston
Houston, Texas, 77079, United States
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MD Anderson in Sugar Land
Sugar Land, Texas, 77478, United States
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MD Anderson in The Woodlands
Conroe, Texas, 77384, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
External Beam Radiation Therapy and Stereotactic Body Radiation Therapy
What this could lead to
If it works, this could offer a way to control cancer that has worsened after immunotherapy, potentially slowing disease progression.
What could go wrong
This is a mid-stage trial, so results are not yet proven. Radiation may cause side effects, and not all patients may benefit.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.