Daily tube flushing may be unnecessary, tiny study hints
NCT ID NCT06987877
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether flushing a nephrostomy tube (a tube that drains urine from the kidney) with salt water every day actually prevents blockages. Twenty adults who have or will get a nephrostomy tube will be randomly assigned to flush daily or not flush at all. Researchers will track tube obstructions over 3 months to see if there is a difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- saline (salt water) flush
- What this could lead to
- If it works, this could show that daily flushing is unnecessary, simplifying care and reducing patient burden.
- What could go wrong
- This is a very small pilot study with only 20 participants, so results may not apply broadly. It is not designed to prove a new treatment, only to gather early data.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: • Age 18-80, with planned nephrostomy tube exchange or new nephrostomy tube placement with ongoing need for a nephrostomy tube. Exclusion Criteria: * Current local infection * History of anaphylaxis to iodinated contrast * Pregnant or intent to become pregnant during the study * Irreversible coagulopathy * Planned for definitive treatment for the clinical indication of the nephrostomy tube prior to 12-week post-intervention. * Planned routine exchange prior to 12 weeks after nephrostomy tube exchange or placement procedure * Complete sensory loss below T10 dermatome.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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