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Nebulizer vs inhaler: which delivers asthma relief faster?

NCT ID NCT05977699

Symptom relief Sponsor: University of Saskatchewan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two methods of giving salbutamol (a common asthma rescue drug) to 16 adults with mild asthma. One method used a vibrating mesh nebulizer, the other a standard inhaler with a spacer. The goal was to see which one reversed airway narrowing faster and more completely. Results will help guide choices for delivering quick relief during asthma attacks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
salbutamol
What this could lead to
If successful, this could show that a vibrating mesh nebulizer works as well as or better than a standard inhaler for quickly reversing asthma symptoms.
What could go wrong
This is a very small, early-phase study with only 16 people, so results may not apply to everyone. It only looks at short-term lung function, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

16 people

The number who actually took part.

Started

Jan 2024

Finished

Nov 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age (years) at least 18, male or female * no confounding health issue (i.e. no health conditions, other than asthma, that would put the participant at risk or affect data integrity) * baseline FEV1 ≥ 65% predicted (per Quanjer GLI 2012) * methacholine PD20 ≤ 800mcg Exclusion Criteria: * respiratory infection within 4 weeks of Visit 1 * exposure to triggers of respiratory symptoms within 4 weeks of Visit 1 * currently pregnant or breastfeeding * current smoker (cigarettes, vaping)

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Conditions

The condition(s) this trial relates to.

asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Asthma

Contacts and locations

Locations

  • Asthma Research Lab University of Saskatchewan Room 346 Ellis Hall

    Saskatoon, Saskatchewan, S7N 0W8, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.