Massive AML registry launches to unlock secrets of leukemia
NCT ID NCT03188874
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This registry study is collecting medical information and biological samples from 15,000 adults with acute myeloid leukemia (AML) across 60 German hospitals. Researchers aim to track patient outcomes, treatment patterns, and disease characteristics to better understand AML. No new treatments are being tested; instead, the goal is to gather data that could inform future research and care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could improve understanding of AML and help guide future treatments.
- What could go wrong
- This is an observational registry, not a treatment trial. It will not directly test or provide any new therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 15,000 people
The number the study aims to enrol. It can still change while the study runs.
- Start date
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Sep 2010
- Expected to finish
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Sep 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with newly-diagnosed AML, including acute promyelocytic leukemia (APL)
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * AML according to the WHO (World Health Organization) diagnostic criteria, including acute promyelocytic leukemia * Age ≥ 18 years. There is no upper age limit. * Signed written informed consent Exclusion Criteria: * there are no exclusion criteria
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Acute myeloid leukemia (AML) are added.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
60 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Agaplesion Diakonieklinikum Rotenburg
RECRUITINGRotenburg (Wümme), Lower Saxony, 27956, Germany
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Alexianer St. Hedwig-Krankenhaus
RECRUITINGBerlin, State of Berlin, 10115, Germany
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Alfried Krupp Krankenhaus Rüttenscheid
RECRUITINGEssen, North Rhine-Westphalia, 45131, Germany
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Augusta Kranken Anstalt Bochum
RECRUITINGBochum, North Rhine-Westphalia, 44791, Germany
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Carl-Thiem-Klinikum Cottbus gGmbH
RECRUITINGCottbus, Brandenburg, 03048, Germany
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Diakonie Klinikum Dietrich Bonhoeffer
RECRUITINGNeubrandenburg, Mecklenburg-Vorpommern, 17036, Germany
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Diakonie Klinikum GmbH Jung-Stilling-Krankenhaus
RECRUITINGSiegen, North Rhine-Westphalia, 57074, Germany
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Diakonie-Klinikum
RECRUITINGSchwäbisch Hall, Baden-Wurttemberg, 74523, Germany
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Dr. Horst Schmidt Kliniken GmbH
RECRUITINGWiesbaden, Hesse, 65199, Germany
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Elblandkliniken Stiftung & Co.KG
RECRUITINGRiesa, Saxony, 01589, Germany
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Ev. Diakonie-Krankenhaus gemeinn. GmbH Bremen
RECRUITINGBremen, 28239, Germany
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HELIOS Klinikum Schwerin
RECRUITINGSchwerin, Mecklenburg-Vorpommern, 10955, Germany
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Heinrich-Braun-Klinikum gGmbH
RECRUITINGZwickau, Saxony, 08060, Germany
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Helios Klinikum Berlin-Buch
RECRUITINGBerlin, State of Berlin, 13125, Germany
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Helios Klinikum Duisburg
RECRUITINGDuisburg, North Rhine-Westphalia, 47166, Germany
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Helios Klinikum Duisburg
RECRUITINGDuisburg, North Rhine-Westphalia, 47228, Germany
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Helios Klinikum Erfurt
RECRUITINGErfurt, Thuringia, 99089, Germany
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Johanniter-Krankenhaus Genthin-Stendal
RECRUITINGStendal, Saxony-Anhalt, 39576, Germany
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Kliniken Sindelfingen-Böblingen gGmbH
RECRUITINGSindelfingen, Baden-Wurttemberg, 71065, Germany
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Klinikum Altenburger Land GmbH
RECRUITINGAltenburg, Thuringia, 04600, Germany
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Klinikum Augsburg
RECRUITINGAugsburg, Bavaria, 86156, Germany
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Klinikum Bayreuth GmbH
RECRUITINGBayreuth, Bavaria, 95445, Germany
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Klinikum Chemnitz gGmbH
RECRUITINGChemnitz, Saxony, 09113, Germany
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Klinikum Frankfurt (Oder) GmbH
RECRUITINGFrankfurt (Oder), Brandenburg, 15236, Germany
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Klinikum Fulda / MVZ Osthessen GmbH
RECRUITINGFulda, Hesse, 36043, Germany
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Klinikum Gütersloh
RECRUITINGGütersloh, North Rhine-Westphalia, 33332, Germany
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Klinikum Mannheim GmbH
RECRUITINGMannheim, Baden-Wurttemberg, 68167, Germany
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Klinikum Mittelbaden
RECRUITINGBaden-Baden, Baden-Wurttemberg, 76532, Germany
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Klinikum Nürnberg
RECRUITINGNuremberg, Bavaria, 90419, Germany
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Klinikum St. Georg gGmbH
RECRUITINGLeipzig, Saxony, 04129, Germany
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Klinikum Südstadt Rostock
RECRUITINGRostock, Mecklenburg-Vorpommern, 18059, Germany
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Klinikum Wolfsburg
RECRUITINGWolfsburg, Lower Saxony, 38440, Germany
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Klinikum der Universität zu Köln
RECRUITINGCologne, North Rhine-Westphalia, 50937, Germany
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Krankenhaus Düren gGmbH
RECRUITINGDüren, North Rhine-Westphalia, 52351, Germany
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Krankenhaus Martha-Maria Halle-Dölau
RECRUITINGHalle, Saxony-Anhalt, 06120, Germany
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MVZ Klinikum Coburg GmbH
RECRUITINGCoburg, Bavaria, 96450, Germany
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Marien Kliniken, St. Marien-Krankenhaus
RECRUITINGSiegen, Nordhein-Westfalen, 57072, Germany
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ONKO Medeor Onkologische Zentren
RECRUITINGDonauwörth, Bavaria, 86609, Germany
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Rems-Murr-Klinikum Winnenden
RECRUITINGWinnenden, Baden-Wurttemberg, 71364, Germany
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Robert-Bosch-Krankenhaus GmbH
RECRUITINGStuttgart, Baden-Wurttemberg, 70376, Germany
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Sozialstiftung Bamberg
RECRUITINGBamberg, Bavaria, 96049, Germany
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St. Barbara-Klinik Hamm GmbH
RECRUITINGHamm, North Rhine-Westphalia, 59075, Germany
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St. Bernward Krankenhaus Hildesheim
RECRUITINGHildesheim, Lower Saxony, 31134, Germany
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Stiftungsklinikum Mittelrhein GmbH
RECRUITINGKoblenz, Rhineland-Palatinate, 56068, Germany
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Städt. Kliniken Bielefeld gem. GmbH - Klinikum Mitte
RECRUITINGBielefeld, North Rhine-Westphalia, 33604, Germany
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Städtisches Krankenhaus Kiel GmbH
RECRUITINGKiel, Schleswig-Holstein, 24116, Germany
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Universitätsklinikum Aachen
RECRUITINGAachen, North Rhine-Westphalia, 52074, Germany
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Universitätsklinikum Carl Gustav Carus
RECRUITINGDresden, Saxony, 01307, Germany
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Universitätsklinikum Düsseldorf
RECRUITINGDüsseldorf, North Rhine-Westphalia, 40225, Germany
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Universitätsklinikum Erlangen
RECRUITINGErlangen, Bavaria, 91054, Germany
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Universitätsklinikum Essen
RECRUITINGEssen, North Rhine-Westphalia, 45747, Germany
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Universitätsklinikum Frankfurt
RECRUITINGFrankfurt am Main, Hesse, 60590, Germany
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Universitätsklinikum Gießen und Marburg
RECRUITINGMarburg, Hesse, 35033, Germany
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Universitätsklinikum Halle (Saale)
RECRUITINGHalle, Saxony-Anhalt, 06120, Germany
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Universitätsklinikum Jena
RECRUITINGJena, Thuringia, 07740, Germany
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Universitätsklinikum Leipzig
RECRUITINGLeipzig, Saxony, 04103, Germany
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Universitätsklinikum Münster
RECRUITINGMünster, North Rhine-Westphalia, 48149, Germany
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Universitätsklinikum Schleswig-Holstein
RECRUITINGKiel, Schleswig-Holstein, 24105, Germany
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Universitätsklinikum Würzburg
RECRUITINGWürzburg, Bavaria, 97080, Germany
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Universtitätsklinikum Heidelberg
RECRUITINGHeidelberg, Baden-Wurttemberg, 69120, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a liposomal drug combo improve AML treatment for older adults?
- Can a CDK8/CDK19 blocker help when leukemia and MDS return?
- Can an Anti-Inflammation drug make AML chemotherapy work better?
- Can a new drug trio overcome venetoclax resistance in leukemia?
- Can engineered cells beat relapsed blood cancers?
- Can a new pill outsmart resistant leukemia?