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Heart failure study aims to boost stamina with diabetes drug and nitrate

NCT ID NCT05138575

First seen Apr 25, 2026 · Last updated May 24, 2026 · Updated 7 times

Summary

This study tests whether a diabetes drug (empagliflozin) and a nitrate supplement (potassium nitrate) can help people with a type of heart failure called HFpEF exercise longer. About 53 adults with stable heart failure will take the drugs for a period and then do a treadmill test to measure endurance. The goal is to see if these treatments improve energy use in muscles and blood flow.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pennsylvania Health System

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.