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New drug cocktail shows promise for tough leukemia

NCT ID NCT03900949

First seen Oct 31, 2025 · Last updated May 23, 2026 · Updated 37 times

Summary

This early-phase study tested whether adding two targeted drugs (gemtuzumab ozogamicin and midostaurin) to standard chemotherapy is safe for people with a specific genetic type of acute myeloid leukemia (FLT3-mutated AML). The study involved 21 newly diagnosed patients and aimed to find the best dose with acceptable side effects. While the approach may improve treatment, patients typically need ongoing therapy, so this is not a cure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • Oregon Health and Science University Knight Cancer Institute - Northwest Portland

    Portland, Oregon, 97210, United States

Conditions

Explore the condition pages connected to this study.