New drug cocktail shows promise for tough leukemia

NCT ID NCT03900949

First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 35 times

Summary

This early-stage study tested whether adding two targeted drugs (gemtuzumab ozogamicin and midostaurin) to standard chemotherapy is safe for people with a specific type of acute myeloid leukemia (FLT3-mutated AML). 21 newly diagnosed adults took part. The goal was to find the best dose and check for side effects. While the combination aims to improve treatment, patients still need ongoing management, so this is not a cure.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • Oregon Health and Science University Knight Cancer Institute - Northwest Portland

    Portland, Oregon, 97210, United States

Conditions

Explore the condition pages connected to this study.