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New depression drug passes first safety check in healthy volunteers

NCT ID NCT04981561

First seen Mar 25, 2026 · Last updated May 20, 2026 · Updated 14 times

Summary

This early-stage study tested a single dose of the experimental drug AGN-241751 (zelquistinel) in 68 healthy adults to see if it is safe and how the body processes it. The main goal was to check for side effects, and the study also measured drug levels in the blood. This trial did not treat depression directly but gathered important safety information for future research.

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