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Botox gets a boost: new combo targets wrinkles

NCT ID NCT06834789

First seen Nov 17, 2025 · Last updated May 23, 2026 · Updated 17 times

Summary

This early-stage study tested whether combining a new drug (AGN-151586) with BOTOX is safe for treating moderate to severe frown lines between the eyebrows. 132 healthy adults received a single treatment and were monitored for side effects and immune reactions. The goal was to check safety, not to measure how well it works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Austin Institute for Clinical Research - Pflugerville /ID# 270834

    Pflugerville, Texas, 78660, United States

  • Eye Research Foundation /ID# 270827

    Newport Beach, California, 92663, United States

  • Investigate MD /ID# 270771

    Scottsdale, Arizona, 85260, United States

  • Marcus Facial Plastic Surgery /ID# 270770

    Redondo Beach, California, 90277, United States

  • Skin Research Institute LLC /ID# 270831

    Coral Gables, Florida, 33146-1837, United States

  • SkinDC /ID# 270932

    Arlington, Virginia, 22209, United States

  • Skincare Physicians /ID# 271018

    Chestnut Hill, Massachusetts, 02467, United States

  • Wilmington Dermatology Center /ID# 270828

    Wilmington, North Carolina, 28403, United States

Conditions

Explore the condition pages connected to this study.