Healthy volunteers needed to test two forms of heart failure medicine
NCT ID NCT07476157
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study will test two versions of a drug (AD-118 and AD-1181) in 70 healthy adults to see how they are processed by the body and if they are safe. Participants will receive a single dose of each version under fasting conditions. The study does not aim to treat any disease, but to gather important information for future heart failure research.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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May 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 to 64 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Body weight equal to or greater than 50kg and Body mass index (BMI) between 18.0 kg/m2 and 30.0 kg/m2 at the time of screening visit * Subjects aged 19 years or older and under 65 years at the screening visit Exclusion Criteria: * Participation in another clinical study with an investigational drug within the 6 months from scheduled first administration * Other exclusions applied
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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H PLUS YANGJI HOSPITAL, Seoul
Seoul, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- A gentle electric pulse to the heart: new device tested for heart failure
- Can a heart drug shield the brain? a trial investigates Vericiguat's potential to slow cognitive decline
- Fine-Tuning heart failure drugs to flush out excess salt
- A supplement that could help heart failure patients shed excess fluid?
- Can a wearable predict heart failure Flare-Ups before they happen?