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Could a simple addition to gallbladder surgery help prevent ovarian cancer?

NCT ID NCT07642791

Prevention Sponsor: University of Zurich Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether removing the fallopian tubes during planned gallbladder removal surgery is safe for women aged 45 and older. The goal is to see if this extra step can help prevent ovarian cancer without causing more complications. About 300 women will take part, with half getting the added procedure and half having standard gallbladder surgery alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
opportunistic salpingectomy (removal of fallopian tubes)
What this could lead to
If successful, this could offer a safe way to reduce ovarian cancer risk during routine gallbladder surgery.
What could go wrong
This is a small, early-stage trial focused on safety, not cancer prevention. It may not show a clear benefit or apply to all women.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

300 people

The number who actually took part.

Started

Apr 2026

Expected to finish

May 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women aged 45 years or older. * No known history of ovarian or fallopian tube cancer. * Completed family planning. * Scheduled to undergo elective laparoscopic cholecystectomy for benign gallbladder disease. * Able to provide informed consent. * Willing to comply with study procedures and follow-up assessments. Exclusion Criteria: * Previous abdominal Surgery or any inflammatory bowel disease. * Current pregnancy or breastfeeding (verbally asked). * Contraindications to laparoscopic surgery (e.g., severe cardiopulmonary disease, extensive prior abdominal surgery). * Any medical condition that, in the opinion of the investigator, would preclude safe participation in the study or interfere with follow-up. * Participation in another clinical trial that may confound the results of this study.

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Conditions

The condition(s) this trial relates to.

cholecystolithiasis ovarian cancer prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cholecystolithiasis Ovarian cancer

Contacts and locations

Locations

  • Division of Visceral Surgery and Transplantation , University Hospital Zurich

    Zurich, 8091, Switzerland

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