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Scientists probe how nerve zaps fix bowel leakage

NCT ID NCT01786304

Knowledge-focused Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how sacral nerve stimulation (SNS) affects the nerves in the gut of people with fecal incontinence. Researchers collected tissue samples from 37 patients who had a stimulator implanted. They wanted to see if the stimulation changes certain nerve cells. The goal was to understand why SNS works, not to test if it works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
sacral nerve stimulation (implanted device)
What this could lead to
If successful, this could explain how sacral nerve stimulation works, potentially leading to better treatments for fecal incontinence.
What could go wrong
This is a small, early-stage study focused on understanding how the treatment works, not on proving it is effective. The results may not lead to new treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

37 people

The number who actually took part.

Start date

Jan 2013

Finished

Nov 2016

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Fecal incotinence * refractory to medial treatment * Eligible to a treatment with sacral nerve stimulation Exclusion Criteria: * age \< 18 yo * age \< 75 yo * anal defect \> 120° * bilateral interruption of the bulbo-cavernous reflex * patient not able to speack and understand the French Language * patient not affilated to the French healthcare system * pregnancy

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Conditions

The condition(s) this trial relates to.

Fecal Incontinence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Fecal incontinence

Contacts and locations

Locations

  • Nantes University Hospital

    Nantes, Pays de Loire, 44000, France

  • Rouen University Hospital

    Rouen, Normandy, 76000, France

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