A nerve block in the lower back may ease pain during scarless gynecologic surgery — a trial puts it to the test
NCT ID NCT07732322
First seen Jul 28, 2026 · Last updated Sep 11, 2026 · Updated 4 times
Summary
This trial tests whether adding a sacral erector spinae plane (ESP) block — a local anesthetic injection near the lower spine — to general anesthesia can reduce pain and opioid use during and after vNOTES, a minimally invasive gynecologic surgery that uses the vagina as a natural opening. The study will compare two groups of adults undergoing elective vNOTES: one receiving general anesthesia alone and one receiving general anesthesia plus the block. Researchers will measure intraoperative opioid consumption, postoperative pain scores, and the amount of additional pain medication needed.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a sacral erector spinae plane (ESP) block — a local anesthetic injection near the lower spine
- What this could lead to
- If effective, this nerve block could offer a way to manage pain during vNOTES surgery while reducing the need for strong opioids.
- What could go wrong
- This is a small, early-stage trial with only 42 participants, so results may not apply broadly. Nerve blocks carry risks such as infection, bleeding, or allergic reaction.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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43 people
The number who actually took part.
- Started
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Jul 2026
- Finished
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Aug 2026
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Ages 18-65 * Planned for elective vNOTES surgery * ASA 1-3 * BMI \<35 Exclusion Criteria: * ASA 4 * Planned emergency surgery * Pregnant patients * Persons with coagulopathy * Persons with allergy to local anesthetics * Persons with neurological disease * Persons with infection in the area where the block will be performed * Persons who refuse to participate in the study for any reason
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ankara Etlik City Hospital
Altındağ, Ankara, 06000, Turkey (Türkiye)
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