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New hope for leukemia patients: drug combo shows promise in early trial

NCT ID NCT04742101

First seen May 24, 2026 · Last updated May 24, 2026

Summary

This study tested a new drug called S65487 combined with azacitidine in 57 adults with untreated acute myeloid leukemia who were not healthy enough for intensive treatment. The goal was to see if the combination is safe and can help achieve complete remission. The trial has completed, and results will show how well the treatment works and what side effects occur.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • C. Universidad de Navarra Servicio de Hematologia

    Pamplona, 31008, Spain

  • H. Universitario La Fe Servicio de Hematologia

    Valencia, 46026, Spain

  • Hospital 12 de Octubre Servicio de Hematología

    Madrid, 28041, Spain

  • Institut Gustave Roussy

    Villejuif, 94805, France

  • Narodowy Instytut Onkologii im. M. Sklodowskiej-Curie Klinika Transplantacji Szpiku i Onkohematologii pokoj 4.041 ul. Wybrzeze Armii Krajowej 15

    Gliwice, 44-102, Poland

  • Samsung Medical Center - Division of Hematology-Oncology

    Seoul, 06351, South Korea

  • Semmelweis Egyetem Belgyógyászati és Onkológiai Klinika Klinikai Farmakológiai Részleg

    Budapest, H-1083, Hungary

  • Seoul National University Hospital - Department of Hematology-Oncology

    Seoul, 03080, South Korea

  • The Christie NHS foundation Trust

    Manchester, M20 4BX, United Kingdom

  • University College London - Hospitals NHS Foundation Trust

    London, NW1 2PG, United Kingdom

  • Western General Hospital

    Edinburgh, EH4 2XU, United Kingdom

Conditions

Explore the condition pages connected to this study.