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Could a common plant compound tame ulcerative colitis?

NCT ID NCT07370220

Disease control Sponsor: Benha University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether rutin, a natural compound found in plants, can help people with ulcerative colitis. 60 adults took rutin tablets or a placebo for 30 days. The goal was to see if rutin reduces gut inflammation and improves symptoms like diarrhea and abdominal pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Rutin (a plant-derived flavonoid) taken as 500 mg oral tablets twice daily for 30 days
What this could lead to
If it works, this could point toward a new, natural treatment option for ulcerative colitis that reduces gut inflammation and improves symptoms.
What could go wrong
This is a small, early-phase trial (60 people) with short follow-up. Results may not apply to all patients, and the benefit over placebo may be modest or absent. Side effects or lack of long-term data are also unknowns.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

60 people

The number who actually took part.

Started

Feb 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of UC confirmed by endoscopy/histology. * Age 18 to 65 years. Exclusion Criteria: * Pregnancy or breastfeeding. * Known hypersensitivity to Rutin. * Presence of other serious systemic diseases (e.g., malignancy, severe hepatic or renal failure).

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ulcerative colitis

Contacts and locations

Locations

  • Benha Faculty of Medicine

    Banhā, Al Qalyoubia, 13511, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.