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New Non-Opioid shot shows promise for stubborn foot pain

NCT ID NCT05695339

First seen Oct 31, 2025 · Last updated May 25, 2026 · Updated 32 times

Summary

This early-phase study tested a non-opioid drug called resiniferatoxin (RTX) for people with Morton's neuroma, a nerve condition causing burning or shooting foot pain. Three adults who had not found relief from standard treatments received a single injection into the painful foot area. The main goal was to check safety and side effects over 4 weeks, with pain changes also tracked.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.