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Brain zaps + treadmill training may sharpen stroke recovery

NCT ID NCT07356687

Symptom relief Sponsor: The Hong Kong Polytechnic University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study tests whether a gentle brain stimulation technique called rTMS, given just before walking-and-thinking training, can improve mobility and mental sharpness in people who had a stroke at least 6 months ago. 184 participants will receive either real or fake rTMS before 12 sessions of dual-task training over 3 weeks. Researchers will measure walking speed, balance, and thinking during walking to see if the combo works better than training alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
repetitive transcranial magnetic stimulation (rTMS) combined with dual-task gait training
What this could lead to
If it works, this could point toward a better rehab approach to improve walking and thinking at the same time for people after stroke.
What could go wrong
This is a mid-sized trial testing a non-invasive technique; results may not apply to all stroke survivors, and the benefit over standard training may be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 184 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Jan 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Unilateral ischemic or hemorrhagic hemispheric stroke * Age ≥ 50 years -≥ 6 months post-stroke * Medically stable * Able to walk independently ≥ 1 minute (assistive device allowed) * Able to follow commands * mRS 1-3 * MoCA ≥ 22 Exclusion Criteria: * Other neurological disorders * Cerebellar/brainstem injury * TMS contraindications (e.g., pacemaker, intracranial metal, seizure history, pregnancy) * Contraindications to exercise (e.g., unstable angina) * Severe aphasia (NIHSS item 9 ≥ 2) * Pain/illness limiting performance * Concurrent formal rehabilitation elsewhere * RMT cannot be determined * Fails TMS safety screening

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • The Hong Kong Polytechnic University

    RECRUITING

    Hong Kong, HongKong, HKG, Hong Kong

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