Brain zaps may help Parkinson's patients stay steady on their feet
NCT ID NCT05198076
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether high-frequency repetitive transcranial magnetic stimulation (rTMS) can improve balance in people with Parkinson's disease. Forty participants with mild to moderate Parkinson's will receive 12 sessions over four weeks. Researchers will measure changes in stability and fall risk using a special balance platform.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- High frequency repetitive transcranial magnetic stimulation (rTMS)
- What this could lead to
- If it works, this could offer a non-drug way to improve balance and reduce fall risk in Parkinson's patients.
- What could go wrong
- This is a small, early-stage study with only 40 participants, so results may not apply to everyone. The treatment is non-invasive but may not produce lasting benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Feb 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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55 to 70 years
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All included patients should fulfill the U.K Parkinson's Disease Brain Bank Criteria for idiopathic PD. * Patients with mild to moderate disease severity according to UPRS and Modified Hoehn and Yahr staging * Duration of illness from two to five years were included. * All included patients should be medically and psychologically stable and of adequate cardiac function. * All included patients should haven't receive any rTMS sessions before. * Signed consent form should be taken from all included patients. Exclusion Criteria: * Patients with implanted devices, serious medical illness or history of seizures were excluded. * Patients with severe freezing phenomenon or severe tremors were excluded
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculty of Physical Therapy, Cairo University
RECRUITINGGiza, Ad Doqi, Giza District, Giza Governorate, 11432, Egypt
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Other studies related to the condition(s) this trial covers.
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- Can a workout after walking practice help Parkinson's patients learn better?