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Brain zapping study seeks to unlock rTMS secrets

NCT ID NCT01466439

Knowledge-focused Sponsor: University Hospital, Caen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested how low (1 Hz) and high (20 Hz) frequency repetitive transcranial magnetic stimulation (rTMS) changes brain activity in 30 healthy adults. Participants received both types of stimulation in separate sessions, and their brain waves were measured before and after. The goal was to see if different frequencies have opposite effects on brain inhibition and facilitation, which could help explain how rTMS works for conditions like depression and schizophrenia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
repetitive transcranial magnetic stimulation (rTMS)
What this could lead to
If successful, this could help explain how rTMS works in the brain, potentially improving its use for depression and schizophrenia.
What could go wrong
This is a small, early-phase study in healthy volunteers, not patients. Results may not directly translate to clinical benefits or apply to real-world treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

30 people

The number who actually took part.

Start date

May 2011

Finished

Jun 2013

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * healthy subjects, right-handed, aged from 18 to 60 years * written consent * with social security Exclusion Criteria: * pregnancy, breastfeeding * brain tumor or epilepsy * psychiatric, neurological or ear-nose-throat disorders, current or past * healthy subjects with psychotropic drugs or with substance abuses * healthy subjects with tabacco weaning * protected major with tutor * counter-indication to MRI and rTMS

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Depression Schizophrenia

Contacts and locations

Locations

  • Caen University Hospital, department of psychiatry and explorations fonctionnelles neurologiques

    Caen, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.