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Zapping the brain to unravel Autism's social secrets

NCT ID NCT01648868

Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study used a non-invasive brain stimulation technique called rTMS to investigate how a specific brain area (the superior temporal sulcus) influences social perception in people with autism and healthy controls. Researchers measured changes in eye-gaze patterns and voice recognition after stimulation. The goal was to better understand the brain's role in social cognition, not to treat autism.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Transcranial Magnetic Stimulation (rTMS) device
What this could lead to
If successful, this could help explain how the brain processes social cues, potentially guiding future therapies for autism.
What could go wrong
This is a small, completed study focused on understanding brain function, not a treatment. Results may not lead to direct clinical benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

97 people

The number who actually took part.

Started

Apr 2011

Finished

May 2019

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients with autism * Age from 18 to 30 years old * Autism diagnosed by DSM-IV and ADI-R * IQ \> 60 or able to have an MRI * Social security registration * Consent form signed by patient or legal tutor Healthy controls * Age from 18 to 30 years old * Medical exam previous to the interventions * Social security registration * Consent form signed Exclusion Criteria: All Patients * Indication against MRI (pace-maker, metallic pieces in the body, working with metals) * Indications against rTMS (epilepsy, epilepsy family history, craniotomy scarf, pace maker or neuron stimulator, intraocular or intra-cerebral strange metallic piece, cochlear implant, cardiac valve, chirurgical metallic arterial material, metallic material susceptible to concentrate radio-frequency impulse) * Claustrophobia * Pregnant woman * Women in a fertile age with no efficient contraception method * Use of drugs diminishing cortical excitability * Participation in another clinical trial that forbids the participation in this one * Have already being treated by some electrical or magnetic stimulation technique ( transcutaneous or radicular stimulation)

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Conditions

The condition(s) this trial relates to.

autism spectrum disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Autism spectrum disorder

Contacts and locations

Locations

  • Hôpital Necker-Enfants Malades

    Paris, 75015, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.