Heart valve study aims to cut bleeding risk with routine drug use
NCT ID NCT05774691
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 29 times
Summary
This study compares giving a drug called protamine routinely after a minimally invasive heart valve replacement (TAVI) versus only giving it when needed. The goal is to see if routine use lowers the chance of death or serious bleeding within 30 days. About 1000 adults with aortic valve stenosis will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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A.S.Z. Aalst
RECRUITINGAalst, Belgium
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Amsterdam University Medical Center
NOT_YET_RECRUITINGAmsterdam, Netherlands
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Leiden University Medical Center
RECRUITINGLeiden, South Holland, Netherlands
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Maastricht UMC
NOT_YET_RECRUITINGMaastricht, Limburg, Netherlands
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St. Antonius Hospital
RECRUITINGNieuwegein, Utrecht, Netherlands
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University Hospitals Leuven
RECRUITINGLeuven, Belgium
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Conditions
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