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Robotic knee surgery put to the test in 252-Patient study

NCT ID NCT04338893

First seen Nov 01, 2025

Summary

This study looked at whether using a robotic system (ROSA) during knee replacement surgery leads to more accurate implant placement compared to traditional methods. It included 252 adults with knee pain, arthritis, or deformities who were already scheduled for knee replacement. Researchers measured alignment accuracy with CT scans and also tracked surgery time and patient-reported outcomes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cliniques Universitaires Saint-Luc

    Brussels, Belgium

  • Evangelisches Waldkrankenhaus Spandau

    Spandau, Germany

  • Herzogin Elisabeth Hospital

    Braunschweig, Germany

  • Hôpitaux Universitaires de Genève

    Geneva, Switzerland

  • San Giuseppe Hospital

    Arezzo, Italy

  • The Research Fund of Hadassah Medical Organization

    Jerusalem, Israel

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ROSA Knee System (robotic surgical device) used with Persona, NexGen, or Vanguard total knee implants

What this could lead to

If successful, this could show that robotic-assisted knee replacement leads to more accurate implant placement and better patient outcomes.

What could go wrong

This is a completed post-market study, not a randomized trial, so results may not prove superiority. Robotic surgery may not improve pain or function for all patients.

Conditions

The condition(s) this trial relates to.

Genu Valgum rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.