New study aims to make root canals less painful
NCT ID NCT07196215
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at two ways of cleaning a tooth's root canal to see which one causes less pain afterward. It involves 72 adults with a specific type of tooth nerve pain in their front teeth. Participants will have their root canals cleaned using one of two methods, then rate their pain after 24 and 48 hours.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 72 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Jan 2026
An estimate. Start dates often move.
- Expected to finish
-
Jan 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
20 to 50 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Patients in good health with no systemic disease (ASA Class I or II) * Age range is between 20 to 50 years. * Patients diagnosed with symptomatic irreversible pulpitis in maxillary incisor teeth. * Patients who can understand VAS. * Patients who give verbal consent to participate voluntarily in the study. Exclusion Criteria: * • History of systemic disorder. * Pregnant / lactating females (As per medical record/verbally) * Patients who had taken preoperative drugs as anti-inflammatory analgesic or antibiotics. * Patients with swelling or acute peri-apical abscess. * Tooth not suitable for restoration. * Periodontally compromised teeth. * Retreatment cases.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Activation, patient are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a gel or nanoparticles tame tooth pain after pulp treatment?
- Dentists test three sealers to find the most comfortable root canal
- New study aims to make root canals less painful
- New digital tool aims to boost diabetes prevention in prediabetes patients
- New app aims to empower adults born with heart defects
- Blue dye study aims to find the right washout volume for infected knee implants