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Root canal relief? tiny file technique tested for less pain

NCT ID NCT07239752

Symptom relief Sponsor: College of Physicians and Surgeons Pakistan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will test if a technique called 'apical patency'—gently passing a small file just past the root tip during cleaning—can reduce pain after a root canal. 48 adults with a dead nerve and infection in a back molar will be randomly assigned to receive either this technique or standard cleaning. They will rate their pain at several time points over 72 hours. The goal is to see if this simple change makes a difference in post-treatment discomfort.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Apical patency technique (passing a small file slightly beyond the root tip during root canal cleaning)
What this could lead to
If it works, this could give dentists a simple way to reduce pain after root canal treatment.
What could go wrong
This is a small, early-stage trial with only 48 people, so results may not apply to everyone. The technique might not reduce pain at all.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 48 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria:Adult patients aged 18-65 years. Medically healthy, classified as American Society of Anesthesiologists (ASA) Physical Status I or II. Presence of a single permanent molar tooth diagnosed with necrotic pulp and symptomatic apical periodontitis, and indicated for primary root canal treatment. Patients who provide informed written consent to participate in the study. - Exclusion Criteria: Teeth with prior endodontic treatment or complex anatomy (e.g., calcified canals, severe curvature). Patients with significant systemic illness (e.g., uncontrolled diabetes, immunocompromised status) or pregnancy. History of analgesic intake within 72 hours prior to the root canal procedure. Non-restorable teeth, teeth with severe periodontal disease (pocket depth \>5mm), or teeth with root fractures. Exclusion Criteria: \-

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Conditions

The condition(s) this trial relates to.

dental pulp necrosis periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental pulp necrosis Periapical periodontitis

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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