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Could a simple device make root canals less painful?

NCT ID NCT07642349

Symptom relief Sponsor: Prof Nazeer Khan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial investigates whether using an electronic apex locator to determine the exact stopping point during root canal treatment can reduce pain afterward. Participants with a single-rooted tooth needing a root canal are randomly assigned to one of three groups: two groups use the electronic device to guide treatment, and one group uses standard X-ray methods. Pain levels are measured over the first three days after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
electronic apex locator (J Morita Root ZX)
What this could lead to
If successful, this could show that using an electronic apex locator reduces pain after root canal treatment, leading to a more comfortable experience for patients.
What could go wrong
This is a small, early-stage trial with 125 participants, so results may not apply to everyone. Pain is subjective and can vary widely between individuals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

125 people

The number who actually took part.

Started

Apr 2026

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 50 days

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Inclusion Criteria: 1. Mature Permanent teeth with closed apex 2. Single rooted teeth 3. Symptomatic irreversible pulpitis with normal apex 4. Systemic healthy patient ASA I and ASA II 5. Gender male and female 6. Age: 20 to 50 years 5\. Exclusion Criteria: 1. Bizarre morphology 2. Teeth with open apices 3. Pathological root resorption Exclusion Criteria:

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Conditions

The condition(s) this trial relates to.

pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Apical termination point

Contacts and locations

Locations

  • Baqai Medical University

    Karachi, Sindh, 74600, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.