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New drug combo shows promise for Tough-to-Treat lymphoma

NCT ID NCT02232516

First seen Jun 18, 2026 · Last updated Jun 18, 2026

Summary

This study tested a combination of two drugs, romidepsin and lenalidomide, in 30 adults with a rare and aggressive blood cancer called peripheral T-cell lymphoma (PTCL) who had not received prior treatment. The goal was to see if this drug pair could shrink tumors safely, since standard treatments often cause severe side effects and are not very effective. Participants received romidepsin through a vein and lenalidomide as a pill, and their response was tracked with imaging scans.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Weill Cornell Medicine

    New York, New York, 10021, United States

  • Yale University

    New Haven, Connecticut, 06520, United States

Conditions

The condition(s) this trial relates to.

anaplastic large cell lymphoma angioimmunoblastic T-cell lymphoma extranodal nasal NK/T cell lymphoma hepatosplenic T-cell lymphoma Lymphoma, Extranodal NK-T-Cell mature T-cell and NK-cell non-Hodgkin lymphoma mycosis fungoides primary cutaneous T-cell non-Hodgkin lymphoma Sezary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.