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Gene clues may predict who benefits from cancer drug cetuximab

NCT ID NCT01827956

First seen Jan 11, 2026 · Last updated Jun 18, 2026 · Updated 18 times

Summary

This study looked at whether small differences in certain genes (FCγRIIIA and FCγRIIA) can predict how well the drug cetuximab works in people with advanced head and neck cancers that cannot be cured by surgery or radiation. Researchers analyzed blood samples from 121 participants to check for these gene variations and then tracked how long the cancer stayed under control. The goal was to find a way to personalize treatment, but the study was observational and did not test a new therapy.

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Contacts and locations

Locations

  • Institut Bergonié

    Bordeaux, Aquitaine, 33000, France

Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma upper gum cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.