Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Brain scan study seeks clues to dystonia mystery

NCT ID NCT02727361

Knowledge-focused Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how a specific brain chemical system (cholinergic) might be involved in dystonia, a condition causing muscle spasms and abnormal postures. Researchers used PET scans to measure chemical activity in the brains of 40 adults with a genetic form of dystonia (DYT1). The goal was to better understand the disease, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Jan 2016

Finished

Mar 2018

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Man or woman 18 to 75 years, with health insurance European health insurance card (for resident patients in EU), insurance by bilateral social security agreement signed between his country and France (for resident patients outside the EU) * Diagnosis of dystonia DYT1 confirmed by molecular biology (TORSINE- A gene mutation) * Patient who stopped his anticholinergic treatment 48 hours before imaging Exclusion Criteria: * Patients who underwent surgery for deep brain stimulation or under cholinergic treatment. * Presence of a counter-indication for MRI * Presence of a counter-indication for TEP Scan with \[18F\]-FEOBV * Woman premenopausal without effective ongoing contraception (intrauterine device or combined hormonal) * Patient who underwent a PET examination in the previous month * Presence of any health problem preventing travel to the imaging service of the University Hospital * Being under the legal guardianship of another person or being unable to provide consent to participate * Pregnant or breastfeeding woman

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Dystonia are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Dystonia dystonic disorder early-onset generalized limb-onset dystonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dystonia

Contacts and locations

Locations

  • CHU de Bordeaux

    Bordeaux, 33076, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.