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Robots may unlock hidden recovery in Stroke-Damaged arms

NCT ID NCT07768683

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time

Summary

This study tests whether intensive robotic arm training can help people recovering from a stroke improve arm movement and reduce stiffness. Participants will use two types of robotic devices in 12 sessions over four weeks. Researchers will also use a technique called muscle synergy analysis to understand how the brain and muscles work together during rehabilitation, aiming to make therapy more precise and effective.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Upper limb robotic training using end-effector and exoskeleton robots
What this could lead to
If successful, this could point toward more effective, personalized robotic rehabilitation for stroke survivors, improving arm function and quality of life.
What could go wrong
This is a small, early-stage study. Results may not apply to all stroke patients, and the benefits of robotic training over standard therapy are not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

May 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria for healthy subjects * Adult subjects (aged ≥18 years old) * Non orthopaedic condition at upper limb * No neurological or motor impairment Exclusion criteria for healthy subjects * Physical conditions that can alter normal biomechanics * Pregnant or nursing women * No written informed consent * Active implantable devices (e.g., pacemaker) Inclusion criteria for post-stroke subjects * Adult subjects (aged ≥18 years old) * Subjects suffering from subacute and/or chronic stroke disability * Coming from ischemic or hemorrhagic stroke * With a level of motor impairment defined by a minimum residual motion corresponding to Motricity Index ≥ 39. Exclusion criteria for post-stroke subjects * Subjects with a high level of spasticity (Modified Ashworth Scale: In general \>3 except for motorized joints which may be \>2) * Pain in the affected upper limb (Numeric Rating Scale \> 6) * Severe psychiatric disorder * Permanent neurologic symptoms present immediately before stroke * Physical conditions that can alter normal biomechanics (e.g., recent sprains or injuries, etc.) * Pregnant or nursing women * No written informed consent from the patient or the legal representative * Active implantable devices (e.g., pacemaker) * Unstable medical condition

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Villa Beretta Rehabilitation Center

    Costa Masnaga, Italy, 23845, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.