Robots may unlock hidden recovery in Stroke-Damaged arms
NCT ID NCT07768683
First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time
Summary
This study tests whether intensive robotic arm training can help people recovering from a stroke improve arm movement and reduce stiffness. Participants will use two types of robotic devices in 12 sessions over four weeks. Researchers will also use a technique called muscle synergy analysis to understand how the brain and muscles work together during rehabilitation, aiming to make therapy more precise and effective.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Upper limb robotic training using end-effector and exoskeleton robots
- What this could lead to
- If successful, this could point toward more effective, personalized robotic rehabilitation for stroke survivors, improving arm function and quality of life.
- What could go wrong
- This is a small, early-stage study. Results may not apply to all stroke patients, and the benefits of robotic training over standard therapy are not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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50 people
The number who actually took part.
- Started
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May 2025
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria for healthy subjects * Adult subjects (aged ≥18 years old) * Non orthopaedic condition at upper limb * No neurological or motor impairment Exclusion criteria for healthy subjects * Physical conditions that can alter normal biomechanics * Pregnant or nursing women * No written informed consent * Active implantable devices (e.g., pacemaker) Inclusion criteria for post-stroke subjects * Adult subjects (aged ≥18 years old) * Subjects suffering from subacute and/or chronic stroke disability * Coming from ischemic or hemorrhagic stroke * With a level of motor impairment defined by a minimum residual motion corresponding to Motricity Index ≥ 39. Exclusion criteria for post-stroke subjects * Subjects with a high level of spasticity (Modified Ashworth Scale: In general \>3 except for motorized joints which may be \>2) * Pain in the affected upper limb (Numeric Rating Scale \> 6) * Severe psychiatric disorder * Permanent neurologic symptoms present immediately before stroke * Physical conditions that can alter normal biomechanics (e.g., recent sprains or injuries, etc.) * Pregnant or nursing women * No written informed consent from the patient or the legal representative * Active implantable devices (e.g., pacemaker) * Unstable medical condition
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Villa Beretta Rehabilitation Center
Costa Masnaga, Italy, 23845, Italy
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Other studies related to the condition(s) this trial covers.
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