Robot therapy helps stroke patients regain arm movement

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Written informed consent must be obtained prior to any screening procedures 2. A first-ever unilateral, supra-tentorial stroke, as defined by WHO (rapidly developing clinical signs of focal (or global) disturbance of cerebral function, with symptoms lasting 24 hours or longer or leading to death, with no apparent cause other than vascular origin) 3. ≥18 years old 4. Being in the chronic phase after stroke, i.e. \> 6 months post stroke 5. Motor impairment in the upper limb, defined as Fugl-Meyer score \>22 out of 66 to demonstrate moderate to full upper limb motor function (patients scoring \<23 out of 66 will not be able to comply with the KINARM protocol) 6. Residual sensory upper limb impairment, defined as Tactile Discrimination Test score \<24 out of 25 7. Impaired functionality, defined as Action Research Arm Test score \<52 out of 57 8. Manageable spasticity for KINARM tasks Exclusion Criteria: 1. Having musculoskeletal and/or other neurological disorders impacting care or prognosis 2. Having severe communication or cognitive deficits that interfere with the protocol 3. Any disorder, which in the investigator's opinion might jeopardise participant's safety or compliance with the CIP 4. Contraindications for robot-based therapy (e.g., uncontrolled epilepsy) 5. Participation in another clinical investigation 6. Having uncontrolled head movements (e.g. tremor), only relevant if participant is willing to receive the additional fNIRS assessments 7. Having any contra-indications for MRI, only relevant if participant is willing to receive the additional MRI assessments: * Pacemaker * Implantable Cardioverter Defibrillator (ICD) * Cochlear implant * Internal Insulin-pump * Deep brain stimulation * Any other metal device in body * Claustrophobia * Having a history of a neuropsychiatric or neurologic disorder before the diagnosis of stroke (e.g., depression, traumatic brain injury) * Use of psychoactive medication before the diagnosis of stroke (e.g., anti-depressive medication) * Use (or history of use) of drugs/alcohol * Being pregnant