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New RNA combo tackles tough liver cancer in early trial

NCT ID NCT05097911

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 31 times

Summary

This early-phase study tests a new RNA-based drug (MTL-CEBPA) combined with two standard immunotherapy drugs (atezolizumab and bevacizumab) in people with advanced liver cancer who have not had prior treatment. The main goals are to find the safest dose and see how the tumors respond. About 33 adults with liver cancer that has spread or cannot be removed will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National University Hospital

    Singapore, Singapore

Conditions

Explore the condition pages connected to this study.