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New weekly shot hopes to tame genetic obesity

NCT ID NCT06239116

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 25 times

Summary

This study tests a new weekly injection called RM-718 in people with obesity, including those with a genetic condition affecting the MC4R pathway (like Prader-Willi syndrome). The main goal is to check the drug's safety and how the body processes it. About 150 participants will take part in this early-stage research.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ann and Robert H. Lurie Children's Hospital of Chicago (Part C and Part D)

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Boston Children's Hospital (Part C only)

    RECRUITING

    Boston, Massachusetts, 021115, United States

  • Brigham and Women's Hospital (Part C and Part D)

    RECRUITING

    Boston, Massachusetts, 02115, United States

  • UAB Pediatric Endocrinology (Part C and Part D)

    RECRUITING

    Birmingham, Alabama, 35233, United States

  • University of Utah Pediatric Endocrine Clinic (Part C and Part D)

    RECRUITING

    Salt Lake City, Utah, 84112, United States

  • Vanderbilt University Medical Center (Part C only)

    RECRUITING

    Nashville, Tennessee, 37232, United States

  • Worldwide Clinical Trials (Part A and Part B)

    COMPLETED

    San Antonio, Texas, 78217, United States

Conditions

Explore the condition pages connected to this study.