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New injection into skull marrow aims to help severe stroke patients

NCT ID NCT07166380

First seen Sep 30, 2025 · Last updated May 21, 2026 · Updated 31 times

Summary

This early-phase study tests an experimental drug called RK-4 in 18 people who have had a severe stroke (large hemispheric infarction) and cannot receive or did not respond to standard clot-removal therapy. The drug is injected directly into the bone marrow of the skull once daily for three days. The main goals are to check if the drug is safe and tolerable, and to measure how it moves through the body. Researchers will also look for early signs of benefit.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing TianTan Hospital

    Beijing, Beijing Municipality, 100070, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.