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Can a lower dose of rivaroxaban be safer for kidney patients on dialysis?

NCT ID NCT05410275

First seen Jun 20, 2026 · Last updated Jun 20, 2026

Summary

This study is testing three different low doses of the blood thinner rivaroxaban in 10 adults on chronic hemodialysis. The goal is to see how the drug behaves in the body and how much it thins the blood, to find a dose that might lower bleeding risks. Participants will take each dose for three days, and researchers will measure drug levels and clotting activity.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • 01-Arauco

    RECRUITING

    Tours, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • 02-TOURS

    RECRUITING

    Tours, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

rivaroxaban

What this could lead to

If successful, this could help determine a safer dose of rivaroxaban for dialysis patients who need blood thinners, potentially reducing bleeding risks.

What could go wrong

This is a very small early-phase study with only 10 participants, so results may not apply to all patients. The drug may still cause bleeding or not work as expected.

Conditions

The condition(s) this trial relates to.

Kidney Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.