New hope for kids with rare lung disease as drug trial advances
NCT ID NCT02562235
First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 38 times
Summary
This study tested the safety and correct dose of the drug riociguat in 24 children aged 6 to 18 with pulmonary arterial hypertension (PAH), a serious lung condition that makes it hard for the heart to pump blood. The children took different doses over several weeks, and researchers monitored side effects, vital signs, and drug levels in the blood. The goal was to find a safe dose for children, not to cure the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Aichi Children's Health and Medical Center
Ōbu, Aichi-ken, 474-8710, Japan
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Azienda Ospedale-Università di Padova - UOC Cardiologia Pediatrica
Padova, Veneto, 35128, Italy
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Clínica Imbanaco S.A.S
Cali, Valle del Cauca Department, 760042, Colombia
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Deutsches Herzzentrum der Charité (DHZC)
Berlin, 13353, Germany
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Gottsegen Gyorgy Orszagos Kardiovaszkularis Intezet
Budapest, 1096, Hungary
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Hacettepe Universitesi Tip Fakultesi
Ankara, 06230, Turkey (Türkiye)
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Instituto Nacional de Cardiología "Ignacio Chávez"
México D.F., Mexico City, 14080, Mexico
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Keio University Hospital
Shinjuku-ku, Tokyo, 160-8582, Japan
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National Cerebral and Cardiovascular Center
Suita, Osaka, 565-8565, Japan
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Operadora de Hospitales Angeles S. A. de C. V.
Huixquilucan, 52763, Mexico
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Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ
Szeged, 6720, Hungary
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The University of Osaka Hospital
Suita, Osaka, 565-0871, Japan
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Universitätsklinikum Heidelberg
Heidelberg, Baden-Wurttemberg, 69115, Germany
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Universitätsklinikum Ulm
Ulm, Baden-Wurttemberg, 89075, Germany
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Veterans General Hospital
Kaohsiung City, 813414, Taiwan
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Wojewodzki Szpital Specjalistyczny - Wroclaw
Wroclaw, 51-124, Poland
Conditions
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