New hope for kids with rare lung disease: drug trial shows promise
NCT ID NCT02562235
First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 35 times
Summary
This study tested the safety of a drug called riociguat in 24 children aged 6 to 17 with pulmonary arterial hypertension (PAH), a rare condition where high blood pressure affects the lungs. The drug was given in doses adjusted for each child's age, sex, and weight. The goal was to see if the drug is safe and how the body processes it, with a long-term extension to monitor ongoing effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Aichi Children's Health and Medical Center
Ōbu, Aichi-ken, 474-8710, Japan
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Azienda Ospedale-Università di Padova - UOC Cardiologia Pediatrica
Padova, Veneto, 35128, Italy
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Clínica Imbanaco S.A.S
Cali, Valle del Cauca Department, 760042, Colombia
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Deutsches Herzzentrum der Charité (DHZC)
Berlin, 13353, Germany
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Gottsegen Gyorgy Orszagos Kardiovaszkularis Intezet
Budapest, 1096, Hungary
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Hacettepe Universitesi Tip Fakultesi
Ankara, 06230, Turkey (Türkiye)
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Instituto Nacional de Cardiología "Ignacio Chávez"
México D.F., Mexico City, 14080, Mexico
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Keio University Hospital
Shinjuku-ku, Tokyo, 160-8582, Japan
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National Cerebral and Cardiovascular Center
Suita, Osaka, 565-8565, Japan
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Operadora de Hospitales Angeles S. A. de C. V.
Huixquilucan, 52763, Mexico
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Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ
Szeged, 6720, Hungary
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The University of Osaka Hospital
Suita, Osaka, 565-0871, Japan
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Universitätsklinikum Heidelberg
Heidelberg, Baden-Wurttemberg, 69115, Germany
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Universitätsklinikum Ulm
Ulm, Baden-Wurttemberg, 89075, Germany
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Veterans General Hospital
Kaohsiung City, 813414, Taiwan
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Wojewodzki Szpital Specjalistyczny - Wroclaw
Wroclaw, 51-124, Poland
Conditions
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