Could one dose of antibiotics during nose surgery be enough?
NCT ID NCT04194216
First seen Apr 30, 2026
Summary
This study compares giving a single dose of antibiotics during rhinoplasty (nose surgery) versus a full course of antibiotics after surgery. The goal is to see if the single dose works just as well at preventing infections. Over 800 adults having nose surgery will take part, and researchers will track infection rates between the two groups.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Facial Plastic and Reconstructive Surgery Clinic
Stanford, California, 94305, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cephalexin or clindamycin (antibiotics)
What this could lead to
If successful, this could show that a single antibiotic dose during surgery is enough to prevent infections, reducing the need for post-surgery antibiotics.
What could go wrong
This is a large trial, but it only looks at infection rates in rhinoplasty. Results may not apply to other surgeries, and the best antibiotic approach may still depend on individual patient factors.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.