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Promising new combo aims to extend life in rare gut cancer

NCT ID NCT07337447

First seen Jan 16, 2026 · Last updated May 19, 2026 · Updated 15 times

Summary

This study tests a new treatment for a rare and fast-growing cancer of the digestive system (neuroendocrine carcinoma). It combines standard chemotherapy (FOLFIRI) with two immunotherapy drugs (zimberelimab and domvanalimab) to see if it helps people live longer. About 122 adults whose cancer has worsened after first treatment will take part. The trial uses a smart design that mixes some historical patient data to speed up research.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Amiens Picardie

    Amiens, France

    Contact

    Contact

  • CHU Avicenne APHP

    Bobigny, France

    Contact

    Contact

  • CHU Caen Normandie

    Caen, France

    Contact

    Contact

  • CHU Dijon

    Dijon, France

    Contact

    Contact

  • CHU Montpellier - Hôpital Saint Eloi

    Montpellier, France

    Contact

    Contact

  • CHU Rouen

    Rouen, France

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    Contact

  • CHU Timone

    Marseille, France

    Contact

    Contact

  • CHU de Bordeaux - Hôpital Haut-Leveque

    Pessac, France

    Contact

    Contact

  • CHU de Grenoble

    Grenoble, France

    Contact

    Contact

  • CHU de Poitiers

    Poitiers, France

    Contact

    Contact

  • Centre Oscar Lambret

    Lille, France

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    Contact

  • Centre Paul Strauss

    Strasbourg, France

    Contact

    Contact

  • HEGP

    Paris, France

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    Contact

  • Hôpital Beaujon

    Clichy, France

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    Contact

  • Hôpital Henri MONDOR

    Créteil, France

    Contact

    Contact

  • Hôpital Robert Debré, CHU de Reims

    Reims, France

    Contact

    Contact

  • Hôpital Saint Antoine APHP

    Paris, France

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    Contact

  • Hôpital Saint Louis APHP

    Paris, France

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    Contact

  • Institut Gustave Roussy

    Villejuif, France

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    Contact

  • Institut Paoli Calmettes

    Marseille, France

    Contact

    Contact

  • Service d'Oncologie Médicale - Hôpital Edouard Herriot - Hospices Civils de Lyon

    Lyon, France

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.