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Can a simple moisturizer beat estrogen for vaginal dryness in breast cancer?

NCT ID NCT01984138

First seen Jan 09, 2026 · Last updated May 24, 2026 · Updated 18 times

Summary

This study looks at two treatments for vaginal dryness in women with estrogen-receptor-positive breast cancer who are taking aromatase inhibitors. About 33 participants will use either a vaginal estrogen ring or a Replens moisturizer for six months. The goal is to see which option better improves dryness and itching, while also checking safety and sexual health.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Houston Methodist Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.