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New trial tests clot removal for severe brain vein blockage

NCT ID NCT07548346

First seen Apr 24, 2026 · Last updated May 24, 2026 · Updated 5 times

Summary

This study tests whether removing blood clots from the brain's veins (endovascular thrombectomy) plus standard blood-thinning medication works better than medication alone for people with severe cerebral venous sinus thrombosis (CVST). The trial will include 440 adults at high risk of poor outcomes, such as those with bleeding or brain injury. Participants are randomly assigned to one of two groups, and the main goal is to see if more people achieve functional independence after 12 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Aga Khan University

    Karachi, Pakistan

  • Ain Shams University

    Cairo, Egypt

  • Alexandria University, Smouha Comprehensive Stroke Center

    Alexandria, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Amman Specialized IR Center

    Amman, Jordan

  • Cairo University

    Cairo, Egypt

  • Centre Hospitalier Universitaire Ibn Sina de Rabat

    Rabat, Morocco

  • Department of Neurology, Eskisehir Osmangazi University

    Eskişehir, Turkey (Türkiye)

  • Institut National de Neurologie

    Tunis, Tunisia

  • King Abdulaziz Medical City

    Jeddah, Saudi Arabia

  • King Abdullah Medical City

    Mecca, Saudi Arabia

  • King Khalid University

    Abhā, Saudi Arabia

  • Neurology Department, Al-Azhar University

    Cairo, Egypt

  • Neurology Department, Dr. Lutfi Kirdar City Hospital

    Istanbul, Turkey (Türkiye)

  • Weill Cornell Medicine-Qatar

    Doha, Qatar

Conditions

Explore the condition pages connected to this study.