Eye cancer survivors: does treatment choice impact Long-Term happiness?
NCT ID NCT03662776
First seen Jun 25, 2026 · Last updated Sep 09, 2026 · Updated 4 times
Summary
This study looks at children and teens who survived retinoblastoma in one eye. Researchers want to see if those who had chemotherapy injected into the eye artery have a different quality of life than those who had the eye removed. Participants and their parents will fill out surveys about emotional and behavioral health. The goal is to learn which treatment may lead to better long-term well-being.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors choose treatments that better preserve quality of life for children with retinoblastoma.
- What could go wrong
- This is an observational study, not a treatment trial. It only looks at past treatments and cannot prove cause and effect. Results may not apply to all survivors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2018
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Eligible survivors of unilateral retinoblastoma will be identified via the MSK and TCH databases and offered participation in the study.
- Ages
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8 to 17 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Ability to speak and understand English or Spanish * Diagnosis of unilateral retinoblastoma at any age, confirmed by the enrolling institution * Treatment of retinoblastoma between 2006 or later * Patients must between the age of 8-17 years old * At least 1 year since completion of all cancer-directed therapy * Treatment with enucleation of the affected eye or intra-arterial chemotherapy Parent of patient: * Ability to speak and understand English or Spanish * Ability to confirm that he or she is the parent of a child treated for unilateral retinoblastoma who meets the eligibility criteria listed above * Ability to provide informed consent Exclusion Criteria: * Patients, or parents of patients, treated with both enucleation and intra-arterial chemotherapy are not eligible
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Texas Children's Hospital (Data Collection)
Houston, Texas, 77030, United States
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