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Can eye scans reveal hidden clues about diabetes damage?

NCT ID NCT07747428

Knowledge-focused Sponsor: Sohag University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This study uses a special eye imaging technique called OCT angiography to look at tiny blood vessels in the retina of people with diabetic retinopathy. Researchers will measure vessel density and other vascular features, then check whether these relate to visual sharpness and blood sugar control (HbA1c) across different stages of the disease. The goal is to better understand how diabetes alters retinal blood flow and what that means for vision.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could improve understanding of how diabetes damages the retina, potentially guiding earlier detection or better monitoring of diabetic retinopathy.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Results may not apply to all patients, and the findings are exploratory rather than definitive.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients (18-80 years) with diabetic retinopathy attending the Ophthalmology Department, Sohag University Hospital, who meet the eligibility criteria and undergo OCT angiography and complete ophthalmic examination.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- Inclusion Criteria: * Adults aged 18 to 80 years. * Patients diagnosed with diabetic retinopathy. * Ability to undergo complete ophthalmic examination including OCT and OCT angiography. * Availability of HbA1c measurement within the study period. * Ability and willingness to provide written informed consent. Exclusion Criteria: * Previous vitreoretinal surgery. * Significant media opacity affecting image quality (e.g., dense cataract or vitreous hemorrhage). * Other retinal vascular diseases (e.g., retinal vein occlusion). * Glaucoma or optic nerve diseases affecting visual function. * High myopia (\>6 diopters). * Poor-quality OCTA images due to motion artifacts or poor fixation. * Refusal or inability to provide informed consent. Exclusion Criteria: \-

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Conditions

The condition(s) this trial relates to.

diabetic retinopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diabetic retinopathy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sohag Ophthalmology Hospital

    RECRUITING

    Sohag, Egypt

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