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Retina surgery without eye drops: a game changer or risky move?

NCT ID NCT07396831

Knowledge-focused Sponsor: Loma Linda University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether antibiotic eye drops are necessary after retina surgery to prevent infection. 48 adults having retina surgery were followed for 30 days without using antibiotic drops, though they still used steroid drops. The goal was to see if skipping antibiotics is safe. The study was terminated early, so the results are not conclusive.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could show that skipping antibiotic drops after retina surgery is safe, simplifying recovery and reducing costs.
What could go wrong
The study was terminated early with only 48 participants, so results are limited. Infection risk may still exist, and findings may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

48 people

The number who actually took part.

Started

Apr 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients from a single vitreoretinal surgeon at Loma Linda University Medical Center.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients undergoing Pars plana vitrectomy and/or scleral buckling Exclusion Criteria: * Patients younger than 18 * Patients undergoing Pars plana vitrectomy for endophthalmitis * Patients having combined intraocular lens and vitrectomy surgery * Patients that received a cornea scrape during surgery

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Infection prophylaxis Pars plana vitrectomy Scleral buckling Surgical outcomes

Contacts and locations

Locations

  • Loma Linda University Eye Institute

    Loma Linda, California, 92354, United States

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