Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can a gentler oxygen flow keep breathing steady during eye surgery?

NCT ID NCT04055077

Disease control Sponsor: University of Split, School of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 17, 2026 · Last updated Sep 01, 2026 · Updated 3 times

Summary

This trial tests whether high-flow nasal oxygenation (HFNO) keeps breathing and oxygen levels steadier than standard low-flow nasal oxygenation (LFNO) in patients undergoing sedated vitrectomy, a type of eye surgery. Participants are normal-weight adults with different anesthesia risk levels. The study compares how well each oxygen method maintains blood oxygen and carbon dioxide levels, breathing pattern, heart rate, and blood pressure during the procedure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High-flow nasal oxygenation (HFNO) compared with low-flow nasal oxygenation (LFNO) during sedated eye surgery
What this could lead to
If HFNO proves better at maintaining stable breathing and oxygen levels during sedated eye surgery, it could become the preferred oxygen method for higher-risk patients.
What could go wrong
This is a single-center trial with a modest number of participants, and results may not apply to all surgical settings. HFNO may also cause discomfort or not significantly outperform standard low-flow oxygen.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

176 people

The number who actually took part.

Started

Jun 2022

Finished

Sep 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * normal weight ASA patients of risk class I, II and III * moderate multimodal analgo-sedatiom * pars plana vitrectomy Exclusion Criteria: * Conventional vitrectomy * Obesity * Diseases of peripheral blood vessels * Hematological diseases * Psychiatric diseases * Sideropenic anemia * Patient's refusal * Ongoing chemotherapy or irradiation * remifentanyl and benzodiazepine allergies

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Airway management are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Hypoxia respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Airway management High flow nasal oxygenation Hypoxia Moderate sedation Noninvasive ventilation Pars plana vitrectomy Respiratory complications Respiratory insufficiency Respiratory stability Vitrectomy

Contacts and locations

Locations

  • University clinical hospital centre Zagreb, Croatia

    Zagreb, 10000, Croatia

More trials for these conditions

Other studies related to the condition(s) this trial covers.