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Red wine compound gel may ease pain after gum surgery

NCT ID NCT06521333

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a gel made from resveratrol (a compound found in red wine) could reduce pain after a gum graft procedure better than a hyaluronic acid gel. Thirty adults who needed gum grafts were given one of the two gels applied to the wound. Pain levels were recorded daily for a week. The goal was to see if resveratrol could be a better option for managing post-surgery pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Resveratrol-based gel
What this could lead to
If it works, this could offer a more effective way to manage pain after gum graft surgery.
What could go wrong
This is a small, early study with only 30 participants. The results may not apply to everyone, and resveratrol gel might not be better than the standard treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

May 2024

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patient over 18 years of age 2. Systemically healthy 3. Plaque index (PI) and gingival index (GI) less than 15% (Silness \& Löe) 4. Patients with Mucogingival defects scheduled for free gingival graft Exclusion Criteria: 1. Pregnancy or breastfeeding. 2. Occlusal trauma at site of graft. 3. Severe gagging reflex 4. Smokers. 5. Patients allergic to the used materials.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Mucogingival defects

Contacts and locations

Locations

  • Faculty of dentistry, Cairo University

    Cairo, Egypt

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